Association of maternal folic acid consumption with preterm labor: Findings of a cohort study in Iran | ||
Journal of Basic and Clinical Pathophysiology | ||
مقاله 1، دوره 2، شماره 1، اسفند 2013، صفحه 1-6 اصل مقاله (145.01 K) | ||
نوع مقاله: Research Paper | ||
نویسندگان | ||
Shahrzad hadavand1؛ Nafiseh Zafarghandi* 2؛ Farahnaz Torkestani3؛ Ali Davati4؛ Amineh shafeinia5 | ||
1-Assistant professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Shahed University of Medical Science | ||
2Associatet professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Shahed University of Medical Science | ||
3-Associate professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Shahed University of Medical Science | ||
4Assistant professor of Social Medicine | ||
5General Physician | ||
چکیده | ||
Abstract Background and Objective: Nutritional factors are a matter of debate in the etiology of preterm labor. This study was conducted to assess the association of maternal folic acid consumption with preterm labor .comprised and Materials and Methods: This cohort study was conducted on 191 healthy pregnant women in 2009, referring to two teaching hospitals in Tehran (Iran). The folic acid intake was measured and its correlation with preterm labor (premature rupture of membrane, newborn birth weight, and Apgar score) was assessed. Pearson and Spearman correlation tests were used for statistical analysis. Results: The age range of the participants was 19 to 41 years with a mean and standard deviation of 27.8 and 4.4 years, respectively. Birth weight mean of newborns was 3228.64 (± 439.86) g with a gestational age mean of 38.7 (± 1.49) weeks. In 7 cases, 3.7% of the infants were born premature. In the second trimester of pregnancy, the average intake of folic acid was 1.16 (± 0.79) mg. The correlation of folic acid intake with the pregnancy outcomes was not significant. Conclusion: Our findings did not indicate favorable association of folic acid intake with pregnancy outcomes neither for mothers nor for their neonates. We suggest conducting further studies on larger sample sizes and determining serum folate level. | ||
کلیدواژهها | ||
Keywords: Folic acid؛ pregnancy outcome؛ preterm labor؛ prevention؛ Iran | ||
آمار تعداد مشاهده مقاله: 2,155 تعداد دریافت فایل اصل مقاله: 2,066 |